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+49 341 97 32258

Hausadresse:
Fakultät für Mathematik und Informatik
Institut für Informatik
Universität Leipzig
Augustusplatz 10
Paulinum
Raum P 621
04109 Leipzig

Postadresse:
Deisy Gysi
Fakultät für Mathematik und Informatik
Institut für Informatik
Universität Leipzig
Postfach 10 09 20
04009 Leipzig

Dr. Deisy Gysi

Publications

2017

Deisy Morselli Gysi, Andre Voigt, Tiago Miranda Fragoso, Eivind Almaas and Katja Nowick
wTO: Computing Weighted Topological Overlaps (wTO) & Consensus wTO Network
CRAN
An R package to compute weighted Topological Overlap and consensus.
Link to CRAN

2018


Lisa Kutsche, Deisy Morselli Gysi, Joerg Fallmann, ..., Johan Jakobsson, Katja Nowick, Volker Busskamp
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis
Cell Systems
https://doi.org/10.1016/j.cels.2018.08.011

Deisy Morselli Gysi, Andre Voigt, Tiago Miranda Fragoso, Eivind Almaas and Katja Nowick
wTO: an R package for computing weighted topological overlap and consensus networks with an integrated visualization tool
BMC Bioinformatics
https://doi.org/10.1186/s12859-018-2351-7

Deisy Morselli Gysi, Tiago Miranda Fragoso, Eivind Almaas, Katja Nowick
Comparing multiple networks using the Co-expression Differential Network Analysis (CoDiNA)

Under Review
https://arxiv.org/abs/1802.00828

Deisy Morselli Gysi, Tiago Miranda Fragoso, Eivind Almaas, Katja Nowick
CoDiNA: Co-Expression Differential Network Analysis
CRAN
Categorize links and nodes from multiple networks in 3 categories: Common links (alpha) specific links (gamma), and different links (beta). Also categorizes the links into sub-categories and groups. The package includes a visualization tool for the networks. More information about the methodology can be found at: Gysi et. al., 2018 <arXiv:1802.00828>.
Link to CRAN

Deisy Morselli Gysi, Katja Nowick
RichR: Enrichment for Diseases in a Set of Genes
CRAN
It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) <doi:10.18547/gcb.2016.vol2.iss1.e33>, DisGeNET, Pinero (2016) <doi:10.1093/nar/gkw943> Berto2016, Berto (2016) <doi:10.3389/fgene.2016.00031> and PsyGeNET, Sacristan (2015) <doi:10.1093/bioinformatics/btv301>). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.
Link to CRAN